| Manforce 50 mg is available in tablet form and is typically taken orally with water. The recommended starting dose is usually 50 mg, taken approximately 30 minutes to 1 hour before sexual activity. Depending on individual response and tolerance, the dose may be adjusted by a healthcare provider to a maximum of 100 mg or decreased to 25 mg. Sildenafil Citrate works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. By inhibiting PDE5, Sildenafil allows for increased levels of cGMP, leading to smooth muscle relaxation, vasodilation, and increased blood flow to the penis during sexual stimulation, thereby helping to achieve and maintain an erection. |
