| Understand what microbial ingress is and how microorganisms can enter sterile packaging through microscopic leaks or defects in the container closure system. These pathways allow contamination during storage, handling, or transportation, even when packages appear intact. Preventing microbial ingress is a primary objective of container closure integrity testing (CCIT), as it directly protects sterility, product safety, and shelf life. By identifying and controlling leak pathways, CCIT helps ensure that sterile pharmaceutical and medical device products remain protected throughout their intended lifecycle. |
